United now had a lead to protect as Tottenham pushed for an equaliser in the second half and the hosts created a hat-full of chances, however, they failed to get past the in-form De Gea between the United sticks.
United have real momentum and their bid to claim a Champions League place is gathering pace.
"He is the best goalkeeper in the world, I have said it many times".
"I am so pleased and I'm proud", he added to Sky Sports.
"We won the game against a top team, we controlled the first half but in the second half they had chances", De Gea said. They may still be six points behind Chelsea, who beat Newcastle United 2-1 yesterday, but United have closed the gap to Spurs to seven points and it has forced the bookmakers to slash United's odds for a top-four finish.
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"It was Tottenham against Manchester United", he told his post-match news conference.
"We all enjoy playing football, playing together and that's what we did today".
"I am happy because the performance was unbelievable", stated Mauricio at Wembley.
The Norwegian coach set-up his team perfectly in the first half as United frustrated Tottenham for long periods and hit them with the ideal counter-attack to take the lead shortly before the break.
After talk in the build-up to the game that the match was an opportunity for Pochettino - linked to the United job - to take on interim Old Trafford boss Solskjaer, the Tottenham manager was asked how he felt he fared.
Pochettino also appeared to hint that his side may need reinforcements after Harry Kane limped off with an injury at the end of the game.