"The UK's aerospace sector now stands at the precipice", Enders said in a video released on Airbus' website. It employs more than 6,000 people with many thousands more employed indirectly.
It's very much a case of the perky pound braving through impediments as odds of a no-deal Brexit diminishes and chances of a second referendum taking place slowly increases. "I can reiterate our commitment to the Good Friday Agreement, support to peace and trans-border cooperation, but a no-deal Brexit will clearly, clearly put most of these things at risk".
'The United Kingdom in a no-deal scenario will face enormous difficulties.
The aviation giant's relationship with the European Union has itself been under scrutiny recently, with the World Trade Organization past year ruling the firm received improper subsidies from the bloc after the USA argued it had given $22 billion in state aid to help launch the A380 and A350 jets.
"Sterling continues strengthening and reached the highest level against Euro since 2Q17 in response to the news that the DUP is shifting its support towards PM May's deal", says Petr Krpata, a strategist at ING Group.
"However, aerospace is a long-term business and we could be forced to redirect future investments in the event of a no-deal Brexit".
"And make no mistakes, there are plenty of countries out there who would love to build the wings for Airbus aircraft".
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The economy would only escape a bigger hit this year because growth is expected to remain strong in the first three months of the year, before Britain's scheduled departure.
With just 64 days to the UK's default departure from the union, the global trade secretary flagged talks with counterparts from South Korea, Canada, Israel and Colombia for his trip to the World Economic Forum at Davos.
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The firm said it was making the move because of the growing importance of the Asian market, rather than because of Britain's impending European Union exit.
Britain's main business lobby has warned of disruption to the economy and delays for cross-border trade if Britain leaves the European Union without a transition deal.
But she added: "Unfortunately we are rolling ever closer to the edge of a cliff".
Anti-Brexit protesters outside the Houses of Parliament in London on January 21.
Brexit Minister Chris Heaton-Harris said: "It does beg the reply that why on earth is he not then backing the deal that delivers the certainty all of those businesses he named have asked for?"
May's government has rejected both ideas.
After five leading business organisations said they are "watching in horror" at Westminster politics preventing progress on Brexit, Airbus chief executive Tom Enders said on Thursday it is a "disgrace" that companies are still unable to plan ahead.
Mr O'Donovan told RTÉ's Six One News that Mr Varadkar's comments this morning were articulating the sort of border that we do not want to go back to.
The Associated Press reported this story.