A combination of winds up to 60 miles per hour and heavy rainfall are set to make driving conditions hazardous - including along the coast at times of high tides.
Meteorologists have upgraded their weather warning from yellow to amber as Wales prepares for the arrival of Storm Callum.
Parts of southern Scotland are set for more dismal weather throughout the rest of today and tomorrow, with persistent heavy rain forecast.
Rainfall totals could reach as high as 150mm over the Brecon Beacons, almost as high as the monthly average of 170mm for Wales. There is the potential for flooding in these areas.
Secretary of State for Wales Alun Cairns has spoken of his sadness at the loss of life during Storm Callum.
The Scottish Environment Protection Agency issued five flood alerts for Friday in Argyll and Bute, Ayrshire and Arran, Dumfries and Galloway, Scottish Borders, Skye and Lochaber and Orkney.
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The strongest winds were reported on the Ards peninsula with areas of counties Down, Armagh and Antrim experiencing the worst of the storm.
Northern Ireland Electricity Networks said 1,000 customers had been left without power, while Electricity North West said four weather-related faults had led to problems for 419 customers in Cumbria and Lancashire.
In Co Armagh, Trafficwatch NI reports that a the Tassagh Road, Keady is blocked by a downed tree, as is the Summerisland Road, Moy, the Kingsmill Road, Whitecross and the Loughgall Road, Portadown is partially closed due to fallen trees. But there had been no confirmation was open again by 10.30am.
A yellow rain warning covers parts of Scotland, the West Midlands and the north west and is in place until midnight.
Storm Callum was the third named storm of the windy season - but no past year has seen three named storms before November 29.
"In addition, leaves and twigs, brought down by the wind, could block drains and culverts, increasing the likelihood of flooding".