Here, Goal takes a look at everything you need to know ahead of Saturday's game.
It is easy to make the case for a "same again" approach from Klopp.
The French side stays in third place with four points, and Red Star remain at the bottom with one point.
It worked, though against modest opposition.
The Welshmen also have injury concers, with Lee Peltier (shoulder) and Nathaniel Mendez-Laing (knee) ruled out and Danny Ward, Aron Gunnarsson and Gary Madine all doubtful.
The fixture will not be broadcast live on UK TV this weekend, as it kicks off at 3pm BST. As ever, you can watch all the action Live & Exclusive via beIN SPORTS Connect.
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The forward suffered a broken thumb during a training session with Senegal last week and subsequently missed Liverpool's 1-0 win over Huddersfield on Saturday evening but has now made a return to training.
Liverpool will be looking to boost their qualification hopes when they welcome Red Star Belgrade to Anfield. "After the first 20 minutes we played a good game; we controlled the game, kept a clean sheet and scored a couple of good goals", continued the Dutchman, who was the stand-in skipper on the night.
Klopp has repeatedly stressed he has not been concerned about Salah's performances, and said of the milestone: "I think he would say thanks to his team-mates because it's quite hard to score goals without these wonderful passes, crosses".
The Senegal global made a brisk start to the Premier League season after Mane scored in Liverpool FC's opening three Premier League games.
He scored his first Cardiff goal last weekend as the Bluebirds beat Fulham 4-2 to claim a first league win and climb out of the relegation zone. Drawn in a group alongside Liverpool, Napoli and PSG, the Serbians were always unlikely to advance further in the competition and the latest result makes their task all the more hard.
Yet half a year on, Salah's fortunes are very different at Liverpool.
"He was electric and exciting and scored goals".